Friday, December 18, 2009

801.2403 Topics in Research of Physical Anthropology

Evolution of Infectious Pathogens

INFORMATION

Class Hours: AM 9:00-10:00 (Thu) for every lecture except for May 13 (PM 7:00-8:00); and May 21 (PM 1:00-5:00)
Location: ANATOMY ROOM #212
Credit: 3
Textbook: Emerging Pathogens (edited by Greenblatt C and Spigelman M)

SCHEDULE

Day 1: Mar 18
Chapter 1
*Margulis L, Dolan MF, Guerrero R. The chimeric eukaryote: origin of the nucleus from the karyomastigont in amitochondriate protists. Proc Natl Acad Sci U S A. 2000 Jun 20;97(13):6954-9. (for understanding infection and symbiosis in cell evolution)

Day 2: Mar 25
Chapter 2 to 4

Day 3: Apr 1
Review of Mycobacterium infection in ancient population (by Oh CS)
*Donoghue HD et al. Tuberculosis: from prehistory to Robert Koch, as revealed by ancient DNA. Lancet Infect Dis. 2004 Sep;4(9):584-92.

Day 4: Apr 15
Chapters 12 and 15 (by Oh CS)

Day 5: Apri 22
Chapters 6 and 7

Day 6: Apr 29
Chapters 8 and 9

Day 7: May 6
Chapters 10 and 11

Day 8: May 13
Special lecture: "Tomb of Akeldema and the shroud of Jerusalem" by Dr. Mark Spigelman (Editor/author of the textbook, Israel)

Day 9: May 21
Special lectures on paleoanthropology in 18th Federation Meeting of Korean Basic Medical Scientists

Day 10: June 3
Chapters 13 and 14

Day 11: June 10
Chapters 16 and 17

OTHER SELECTED PAPERS

Hershkovitz I et al. Detection and molecular characterization of 9,000-year-old Mycobacterium tuberculosis from a Neolithic settlement in the Eastern Mediterranean. PLoS One. 2008;3(10):e3426. Epub 2008 Oct 15.

Donoghue HD. Human tuberculosis--an ancient disease, as elucidated by ancient microbial biomolecules.Microbes Infect. 2009 Dec;11(14-15):1156-62. Epub 2009 Aug 29.

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